The Shared Equal Access Regional Cancer Hospital (SEARCH) database is a database of prostate cancer patients at five Veterans Affairs hospitals across the country including the San Diego, CA Greater Los Angeles, CA, Palo Alto, CA, San Francisco, CA, Portland, OR, Augusta, GA, Asheville, NC, and Durham NC Centers. The database is associated with prominent research institutions including Duke University; University of California, San Diego; David Geffen School of Medicine at UCLA; University of California, San Francisco; Oregon Health Sciences University; and Georgia Regents University. The purpose of the SEARCH database is to take full advantage of the strength of the VA population for prostate cancer and the VA electronic medical record system for research purposes. The SEARCH database was formed in late 2000 under the leadership of Dr. Freedland, and the group published their first paper on the role of race predicting prostate cancer outcomes after radical prostatectomies in October 2002. Since that time, the group has published 79 manuscripts including 1 in Journal of the American Medical Association, 2 in the Journal of Clinical Oncology, and 3 in European Urology (the top rated Urology journal in the world); amounting to a new manuscript every other month for the past 11+ years. The current core sites within SEARCH include the VA medical centers in San Diego, CA, Greater Los Angeles, CA, Palo Alto, CA, San Francisco, CA, Portland, OR, Augusta, GA, Asheville, NC, and Durham, NC. We have a dedicated full-time staff including one full-time senior database manager and 4 full-time junior data techs. Due to the strength of the VA system, the database team, which sits at the Durham VA Medical Center, has access to all electronic medical records for all subjects in the entire VA system. Thus, from one central location, we are able to track the outcomes of all men with prostate cancer in SEARCH. It is this type of centralization combined with the strong drive of the SEARCH investigative team that has resulted in 79 manuscripts to date. Though to date our efforts have largely been focused on radical prostatectomy patients, we are actively in the process of expanding the database to include all men diagnosed with prostate cancer at all sites.